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A clnical trial to study the effects of an oral pill containing cyproterone acetate on various clinical and biochemical parameters of polycystic ovary syndrome.

Effects of combination of ethinyl oestradiol with cyproterone acetate on clinical and biochemical parameters in women with polycystic ovary syndrome.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2009/091/000392
Enrollment
30
Registered
2010-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Polycystic ovary syndrome, clinical and biochemical changes

Interventions

Intervention1: Ethinyl oestradiol with cyproterone acetate: 1 tab daily for 21 days then 7 days gap and to restart- for 6 months then evaluations and further 12 months. Control Intervention1: nil: A c

Sponsors

DRSUDHINDRA MOHAN BHATTACHARYAConsultant SCDas Memorial Medical and Research Center Kolkata
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Polycystic ovary syndrome, as per Rotterdam criteria. age- 16-40 years.

Exclusion criteria

Exclusion criteria: Secondary causes of hyperandrogenism, as per Rotterdam criteria; history of hormone intake in the preceding 3 months; medical conditions contraindicated for combined hormone therapy.

Design outcomes

Primary

MeasureTime frame
Chages in clinical parameters like BMI, Waist-hip ratio; acbominal circumference; hirsutism score ; acne lesions; changes in serum total testosterone, SHBG(sex hormone binding globulin levels), Free androgen index,; insulin resistance as measured by fasting glucose- insulin ratio.Timepoint: First time of assessment - 6 months Second time of assessment - 12 months after start of the treatment—

Secondary

MeasureTime frame
side effects and compliance with the medicationTimepoint: first after 6 months and finally after 12 months.—

Countries

India

Contacts

Public ContactDRSUDHINDRA MOHAN BHATTACHARYA

Consultant, S.C.Das Memorial Medical and Researech Center, Kolkata

drsudhindra54@gmail.com033-24836330

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026