A clinical trial to determine whether local application of autologous bone marrow injections can help in healing chronic wounds

A randomised controlled clinical trial to investigate the role of autologous bone marrow derived cells in the healing of chronic wounds

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2009/091/000250

Enrollment

Registered

2009-05-15

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Local injection of autologous bone marrow derived cells: 5 cc processed cells injected Control Intervention1: Local injection of autologous peripheral blood: 5 cc injected

Eligibility

Inclusion criteria

Inclusion criteria: Male or female patients with chronic wounds that had not healed for 3 months or more. Wounds where primary closure could not be achieved. Wounds which were unsuitable for skin grafting.

Exclusion criteria

Exclusion criteria: Wounds with active infection defined as copious pus discharge from the wound. Wounds where distal pulses were not palpable Wounds more than 15 cm in any one dimension. Patients with Hansen?s disease. Patients who were pregnant. Patients who were on chemotherapy. Patients who were diagnosed with hematological disease.

Design outcomes

Primary

Measure	Time frame
Rate of wound healing as defined by a decrease in wound size over timeTimepoint: Follow up every 2 weeks for 3 months	—

Secondary

Measure	Time frame
Standardization of technique of local application of bone marrow cells to chronic woundsTimepoint: Follow up every 2 weeks for 3 months	—

Countries

India

Contacts

Public ContactBenjamin Perakath

Professor

sur5@cmcvellore.ac.in0416-2282085

Outcome results