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A clinical trial to compare the effects of Misoprostol(per rectal) and Oxytocin(intravenous infusion)in reducing blood loss in women undergoing caesarean section.

A randomised double- blind well controlled clinical trial to compare the efficacy and safety of rectally administered Misoprostol and Intravenous Oxytocin infusion in preventing intraoperative and postpartum blood loss in women undergoing caesarean section. - Misoprostol,rectal,blood loss,cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2009/091/000075
Enrollment
Unknown
Registered
2009-04-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Healthy women without known risk factor for Postpartum Haemorrhage are studied.

Interventions

Intervention1: Misoprostol is given rectally after peritonium is opened during LSCS.: Dose of Misoprostol-800 microgram. Control Intervention1: Oxytocin infusion started immidiately after delivery of

Sponsors

Chittaranjan Sevasadan HospitalSPMukherjee Road Kolkata
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: women undergoing elective or emergency caesarean section.

Exclusion criteria

Exclusion criteria: Antepartum Haemorrhage,Severe Preeclampsia,Prolonged and Obstructed labour,Hb below 8gm/dl,Multiple Pregnancy,Polyhydramnios and associated Myoma of uterus,Cardiovascular,renal ,hepatic and connective tissue disorders.

Design outcomes

Primary

MeasureTime frame
blood loss during operation and 8 hours postpartum and change in the hemoglobin 24 hours after delivery.Timepoint: Blood loss:during operation and upto 8 hours postpartum. Hb :predelivery and 24 hours after delivery.

Secondary

MeasureTime frame
need for additional uterotonic, incidence of side effects and complications, need for blood transfusion and cost of oxytocic.Timepoint: Upto 24 hours postpartum.

Countries

India

Contacts

Public ContactDrPicklu Chaudhuri
picklu.chaudhuri@gmail.com03325797827

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 1, 2026