Health Condition 1: null- labor induction
Conditions
Interventions
Intervention1: Misoprostol: Single 50 micrograms versus multiple 25 micrograms
Intervention2: misoprostol: 50 micrograms single dose
Control Intervention1: misoprostol: 25 micrograms every 6 hours for
Sponsors
Kasturba Medical College
Dr TMA Pai Rotary Hospital
Eligibility
Inclusion criteria
Inclusion criteria: inclusion criteria 1. Women with singleton pregnancy 2. Past date pregnancy of 40 weeks or more 3. At term (between 37 and 42 completed weeks of pregnancy) 4. Cephalic presentation 5. Bishop score 6. Amniotic fluid index > 5 7. Reactive fetal heart rate pattern 8. Membranes could be intact or ruptured
Exclusion criteria
Exclusion criteria: Exclusion criteria were as follows 1. Parity >3 2. Prior uterine scars ( previous cesarean section and myomectomy) 3. Multiple pregnancy 4. Estimated fetal weight > 4500 or < 2000g 5. Abnormal fetal heart rate tracings on non stress test 6. Placenta previa 7. Hypersensitivity to prostaglandins 8. Renal, hepatic or cardiovascular disease 9. Severe asthma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vaginal delivery within 24 hours of induction with misoprostolTimepoint: A primary outcome measure is the interval from the first dose of misoprostol to vaginal delivery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in the Bishop score Time interval from induction to onset of adequate uterine contractions Number of women delivering within 12 hours of induction Mode of delivery,spontaneous vaginal, instrumental delivery or Cesarean section and indications for the same Number of doses of misoprostol used Oxytocin augmentation Incidence of adverse effects: hyperstimulaton, fetal heart rate abnormalities. Incidence of postpartum hemorrhage, Neonatal outcome and patient satisfactionTimepoint: Maternal and neonatal outcome | — |
Countries
India
Contacts
Public ContactManjunath A P
Kasturba Medical College. Manipal University
Outcome results
None listed