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Prognostic value assessment of PSMA-T4 examination in the group of patients with triple-negative breast cancer (TNBC) qualified to radical therapy

Status
Not yet recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2025-525110-29-01
Enrollment
100
Registered
2026-08-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

triple-negative breast cancer

Brief summary

Results of post-operative histopathological examination and immunohistochemical analysis assessing PSMA expression.

Detailed description

The incidence of Adverse Events of grade ≥3 severity (according to CTCAE toxicity grading) and the incidence of Serious Adverse Events, in relation to [99mTc]Tc-PSMA-T4 uptake., Results of genetic testing based on liquid biopsy and their correlation with the degree of [99mTc]Tc-PSMA-T4 uptake., Results of immunohistochemical analysis of PSMA receptor expression in histopathological samples., Results of triple-negative breast cancer (TNBC) molecular subtypes.

Interventions

Sponsors

Narodowe Centrum Badan Jadrowych
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Results of post-operative histopathological examination and immunohistochemical analysis assessing PSMA expression.

Secondary

MeasureTime frame
The incidence of Adverse Events of grade ≥3 severity (according to CTCAE toxicity grading) and the incidence of Serious Adverse Events, in relation to [99mTc]Tc-PSMA-T4 uptake., Results of genetic testing based on liquid biopsy and their correlation with the degree of [99mTc]Tc-PSMA-T4 uptake., Results of immunohistochemical analysis of PSMA receptor expression in histopathological samples., Results of triple-negative breast cancer (TNBC) molecular subtypes.

Outcome results

None listed

Source: EU CTIS · Data processed: Aug 13, 2026