Diabetic foot ulcer
Conditions
Brief summary
Time (in weeks) to wound closure in patients with a DFU using semaglutide versus standard of care treatment.
Detailed description
Rate of >50% reduction in ulcer surface area after 6 week of treatment between study groups (excluding newly formed ulcers), Ulcer surface area and depth at every outpatient clinic (relative to baseline), The change in ankle-brachial index/toe pressure measurements over time (at inclusion, and after wound closure of 6 months of follow-up), Rate of lower limb amputation, Rate of endovascular intervention in lower extremities, Rate of infection
Interventions
Sponsors
Radboud universitair medisch centrum Stichting
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time (in weeks) to wound closure in patients with a DFU using semaglutide versus standard of care treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of >50% reduction in ulcer surface area after 6 week of treatment between study groups (excluding newly formed ulcers), Ulcer surface area and depth at every outpatient clinic (relative to baseline), The change in ankle-brachial index/toe pressure measurements over time (at inclusion, and after wound closure of 6 months of follow-up), Rate of lower limb amputation, Rate of endovascular intervention in lower extremities, Rate of infection | — |
Outcome results
None listed