Is magnesium sulfate an alternative with an analgesic and safety profile equivalent to dexmedetomidine as an adjuvant to ropivacaine in erector block in mastectomy?

Conditions

Breast cancer

Brief summary

Time in minutes between recovery from general anesthesia and the moment the patient requests the first rescue analgesia

Detailed description

total amount of rescue analgesic consumed in the postoperative period during the first 24 hours., Pain level using the validated Visual Analog Scale (VAS) (0 = no pain, 10 = maximum imaginable pain). VAS scores will be recorded at time 0, which is when the patient arrives at the PACU, and subsequently at 2, 4, 8, 10, and 24 hours., heart rate (HR) and mean arterial pressure (MAP), incidence of adverse effects such as nausea, vomiting, bradycardia (HR < 60 bpm), hypotension (SBP < 90 mmHg or < 20% of baseline), respiratory depression, pruritus, and any complications related to the block (e.g., vascular puncture, nerve damage, pneumothorax, local anesthetic toxicity)., Patient satisfaction with postoperative pain management will be assessed using a satisfaction scale of 0 to 100 points (0 = Very dissatisfied with the analgesia provided by the treatment and 100 = totally satisfied with the analgesia provided by the treatment).

Related papers

No related papers found yet.

Interventions

DRUGRopivacaína B. Braun 10 mg/ml solución inyectable EFG

DRUGMAGNESIUM SULFATE

DRUGDEXMEDETOMIDINE

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Time in minutes between recovery from general anesthesia and the moment the patient requests the first rescue analgesia	—

Secondary

Measure	Time frame
total amount of rescue analgesic consumed in the postoperative period during the first 24 hours., Pain level using the validated Visual Analog Scale (VAS) (0 = no pain, 10 = maximum imaginable pain). VAS scores will be recorded at time 0, which is when the patient arrives at the PACU, and subsequently at 2, 4, 8, 10, and 24 hours., heart rate (HR) and mean arterial pressure (MAP), incidence of adverse effects such as nausea, vomiting, bradycardia (HR < 60 bpm), hypotension (SBP < 90 mmHg or < 20% of baseline), respiratory depression, pruritus, and any complications related to the block (e.g., vascular puncture, nerve damage, pneumothorax, local anesthetic toxicity)., Patient satisfaction with postoperative pain management will be assessed using a satisfaction scale of 0 to 100 points (0 = Very dissatisfied with the analgesia provided by the treatment and 100 = totally satisfied with the analgesia provided by the treatment).	—

Measure

Time frame

total amount of rescue analgesic consumed in the postoperative period during the first 24 hours., Pain level using the validated Visual Analog Scale (VAS) (0 = no pain, 10 = maximum imaginable pain). VAS scores will be recorded at time 0, which is when the patient arrives at the PACU, and subsequently at 2, 4, 8, 10, and 24 hours., heart rate (HR) and mean arterial pressure (MAP), incidence of adverse effects such as nausea, vomiting, bradycardia (HR < 60 bpm), hypotension (SBP < 90 mmHg or < 20% of baseline), respiratory depression, pruritus, and any complications related to the block (e.g., vascular puncture, nerve damage, pneumothorax, local anesthetic toxicity)., Patient satisfaction with postoperative pain management will be assessed using a satisfaction scale of 0 to 100 points (0 = Very dissatisfied with the analgesia provided by the treatment and 100 = totally satisfied with the analgesia provided by the treatment).

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Countries

Spain

Outcome results

None listed