Effects of butyrate enemas on postoperative intestinal motility disorders in Hirschsprung’s disease

Status

Not yet recruiting

Phases

Phase 3

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2025-523094-42-00

Acronym

RCAPHM18_0018

Enrollment

Registered

2025-12-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hirschsprung's disease

Brief summary

Time to recovery of bowel function after the curative surgery

Detailed description

Assessmenof postoperative functional intestinal obstructive symptoms, Stool consistency evaluated using the validated ‘Bristol’ stool form scale modified for children, Red carmine total intestinal transit time measured, HAEC episode(s) defined by the HAEC score (Pastor et al., 2009; Frykman et al., 2017) and grading of HAEC (Gosain et al, 2017)., Fecal calprotectin measurement

Interventions

DRUG-

DRUGSodium butyrate 1

DRUG1 g/L sol prep

Eligibility

Sex/Gender

All

Age

0 Years to 17 Years

Design outcomes

Primary

Measure	Time frame
Time to recovery of bowel function after the curative surgery	—

Secondary

Measure	Time frame
Assessmenof postoperative functional intestinal obstructive symptoms, Stool consistency evaluated using the validated ‘Bristol’ stool form scale modified for children, Red carmine total intestinal transit time measured, HAEC episode(s) defined by the HAEC score (Pastor et al., 2009; Frykman et al., 2017) and grading of HAEC (Gosain et al, 2017)., Fecal calprotectin measurement	—

Countries

France

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026