Neonatal respiratory distress syndrome
Conditions
Brief summary
Vital parameters (SpO2, HR and crSO2) during surfactant administration; defined as maximum changes/drop from baseline starting with the beginning of the surfactant administration after insertion of the thin catheter till 15 minutes after the LISA procedure.
Detailed description
SpO2, HR, crSO2 and MABP up to three hours after surfactant administration; defined as maximum changes/drop from baseline starting with the beginning of the surfactant administration after insertion of the thin catheter till three hours after LISA procedure., Need of supplemental oxygen, the amount of bradycardia and hypoxia (in minutes); up to three hours after surfactant administration., Vital parameters until three hours after extubation, assessed every five minutes., Need for a second/repetitive dose of surfactant, Invasive ventilation during the first two days after initial surfactant administration., short-term outcome (morbidity) until discharge or term age dependent on what comes first.
Interventions
DRUGCurosurf® 240 mg Suspension zur endotracheopulmonalen Instillation
Sponsors
Medical University Of Graz
Eligibility
Sex/Gender
All
Age
0 Years to 17 Years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vital parameters (SpO2, HR and crSO2) during surfactant administration; defined as maximum changes/drop from baseline starting with the beginning of the surfactant administration after insertion of the thin catheter till 15 minutes after the LISA procedure. | — |
Secondary
| Measure | Time frame |
|---|---|
| SpO2, HR, crSO2 and MABP up to three hours after surfactant administration; defined as maximum changes/drop from baseline starting with the beginning of the surfactant administration after insertion of the thin catheter till three hours after LISA procedure., Need of supplemental oxygen, the amount of bradycardia and hypoxia (in minutes); up to three hours after surfactant administration., Vital parameters until three hours after extubation, assessed every five minutes., Need for a second/repetitive dose of surfactant, Invasive ventilation during the first two days after initial surfactant administration., short-term outcome (morbidity) until discharge or term age dependent on what comes first. | — |
Countries
Austria
Outcome results
None listed