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An Open-Label, Multicenter Study to Evaluate the Pharmacokinetics and Safety of Xembify versus Gamunex-C in Participants with Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Status
Not yet recruiting
Phases
Phase 3
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2025-522165-30-00
Enrollment
6
Registered
2026-07-07
Start date
Unknown
Completion date
Unknown
Last updated
2026-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)

Brief summary

AUC in the IV Phase: Steady-state AUC of total IgG over a 3-week dosing interval (τ) (i.e., AUC(0−21days) in participants with CIDP, AUC in the SC Phase: Steady-state AUC of total IgG over a weekly SC dosing interval (τ) (i.e., AUC(0−7days)) in participants with CIDP

Detailed description

Steady-state mean trough (pre-dose) concentration of total IgG following IV administration of IGIV-C 10% Q3W or SC administration of IGSC 20% QW.

Interventions

DRUGGamunex® 10%
DRUGXembify 200 mg/ml roztok pro subkutánní injekci

Sponsors

Grifols Therapeutics LLC
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
AUC in the IV Phase: Steady-state AUC of total IgG over a 3-week dosing interval (τ) (i.e., AUC(0−21days) in participants with CIDP, AUC in the SC Phase: Steady-state AUC of total IgG over a weekly SC dosing interval (τ) (i.e., AUC(0−7days)) in participants with CIDP

Secondary

MeasureTime frame
Steady-state mean trough (pre-dose) concentration of total IgG following IV administration of IGIV-C 10% Q3W or SC administration of IGSC 20% QW.

Outcome results

None listed

Source: EU CTIS · Data processed: Jul 8, 2026