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Teclistamab plus autologous lymphocytes infusion for the treatment of relapsed/refractory Multiple Myeloma (TALIM). MM0125

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2025-521827-61-00
Enrollment
52
Registered
2026-04-14
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

refractory/relapsed multiple myeloma

Brief summary

Estimation of the DoR at 18 months from the combination therapy (24 months from the beginning of Te monotherapy).

Detailed description

Response at cycles 5 and every 3 cycles according to the IMWG criteria (15), PFS at 18 months from beginning of therapy with Te and ALI, Overall Survival at 24 months from the beginning of therapy with Te, Safety profile overall and with a focus on CRS according to ASTCT (16) and ICANS according to ASTCT (16)

Interventions

DRUGTECLISTAMAB

Sponsors

Fondazione Gimema Franco Mandelli Onlus
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Estimation of the DoR at 18 months from the combination therapy (24 months from the beginning of Te monotherapy).

Secondary

MeasureTime frame
Response at cycles 5 and every 3 cycles according to the IMWG criteria (15), PFS at 18 months from beginning of therapy with Te and ALI, Overall Survival at 24 months from the beginning of therapy with Te, Safety profile overall and with a focus on CRS according to ASTCT (16) and ICANS according to ASTCT (16)

Outcome results

None listed

Source: EU CTIS · Data processed: Apr 15, 2026