Geographic atrophy secondary to age-related macular degeneration
Conditions
Brief summary
Slope of change in GA area (square root transformation) as measured by FAF from baseline to Month 12 (expressed in mm/year) in the study eye
Detailed description
Slope of change in GA area (square root transformation) as measured by FAF from baseline to Month 24 (expressed in mm/year) in the study eye; Rate of change in the macular area of photoreceptor loss (defined as an EZ-RPE thickness of 0 μm) assessed by OCT and EZ mapping at Month 12 and Month 24, Proportion of participants with ≥15 letter loss in ETDRS letters in the study eye at 2 consecutive visits or EOS Visit
Interventions
Sponsors
Adarx Pharmaceuticals Inc.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Slope of change in GA area (square root transformation) as measured by FAF from baseline to Month 12 (expressed in mm/year) in the study eye | — |
Secondary
| Measure | Time frame |
|---|---|
| Slope of change in GA area (square root transformation) as measured by FAF from baseline to Month 24 (expressed in mm/year) in the study eye; Rate of change in the macular area of photoreceptor loss (defined as an EZ-RPE thickness of 0 μm) assessed by OCT and EZ mapping at Month 12 and Month 24, Proportion of participants with ≥15 letter loss in ETDRS letters in the study eye at 2 consecutive visits or EOS Visit | — |
Outcome results
None listed