Skip to content

Pneumococcal booster vaccine responsiveness to PCV20 in persons of 78-84 years of age

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2025-521616-19-00
Acronym
IIV-720
Enrollment
120
Registered
2025-07-01
Start date
2025-08-11
Completion date
Unknown
Last updated
2025-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults receiving a profylactic vaccine to prevent pneumococcal infection

Brief summary

PCV20 specific serum IgG, IgM and IgA concentrations pre-PCV20 and 1 month post-PCV20 vaccination

Detailed description

PCV20 specific serum IgG, IgM and IgA pre-PCV20, 1 month and 11 months post-PCV20 vaccination, IgG, IgM and IgA in serum one month post-PCV20 and one month post PPSV23 vaccination, PCV20 specific IgG and IgA concentrations pre-, 1 month and 11 months post-PCV20 vaccination in mucosal lining fluid

Interventions

Sponsors

Rijksinstituut voor Volksgezondheid en Milieu (RIVM)
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Design outcomes

Primary

MeasureTime frame
PCV20 specific serum IgG, IgM and IgA concentrations pre-PCV20 and 1 month post-PCV20 vaccination

Secondary

MeasureTime frame
PCV20 specific serum IgG, IgM and IgA pre-PCV20, 1 month and 11 months post-PCV20 vaccination, IgG, IgM and IgA in serum one month post-PCV20 and one month post PPSV23 vaccination, PCV20 specific IgG and IgA concentrations pre-, 1 month and 11 months post-PCV20 vaccination in mucosal lining fluid

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026