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Cangrelor in endovascular stroke treatment with emergent carotid artery stenting (CANCAS)

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2025-521564-35-00
Enrollment
50
Registered
2025-10-20
Start date
2025-11-06
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemic stroke with intracranial large artery occlusion of the anterior cerebral circulation

Brief summary

Carotid artery stent patency at 24 (+/-6) hours after stenting

Detailed description

Successful cerebral reperfusion according to modified Thrombolysis In Cerebral Infarction (mTICI) scores 2b-3, Clinical stroke severity according to the National Institutes Health Stroke Scale score at 24 (±6) hours and discharge from hospital or day 7, Modified Rankin Scale score at 90 (±14) days after stroke (telephone assessment allowed), Symptomatic intracranial haemorrhage (ECASS III definition), Major bleeding according to ISTH definition, Intracranial haemorrhage PH1, PH2, class 3 according to Heidelberg Bleeding Classification, In-hospital mortality

Interventions

DRUGACETYLSALICYLIC ACID
DRUGCANGRELOR
DRUGCLOPIDOGREL

Sponsors

Medical University Of Graz
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Carotid artery stent patency at 24 (+/-6) hours after stenting

Secondary

MeasureTime frame
Successful cerebral reperfusion according to modified Thrombolysis In Cerebral Infarction (mTICI) scores 2b-3, Clinical stroke severity according to the National Institutes Health Stroke Scale score at 24 (±6) hours and discharge from hospital or day 7, Modified Rankin Scale score at 90 (±14) days after stroke (telephone assessment allowed), Symptomatic intracranial haemorrhage (ECASS III definition), Major bleeding according to ISTH definition, Intracranial haemorrhage PH1, PH2, class 3 according to Heidelberg Bleeding Classification, In-hospital mortality

Countries

Austria

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026