Hyperlipidemia
Conditions
Brief summary
Mean Percent Change from Baseline in Low-Density Lipoprotein Cholesterol (LDL-C) at Week 8 (Enlicitide + Rosuvastatin Versus Placebo)
Detailed description
Mean Percent Change from Baseline in LDL-C at Week 8, Mean Percent Change from Baseline in Apolipoprotein B (ApoB) at Week 8, Number of Participants with One or More Adverse Events (AEs), Number of Participants who Discontinue Study Drug Due to One or More AEs, Mean Percent Change from Baseline in LDL-C at Week 12, Mean Percent Change from Baseline in Non-High-Density Lipoprotein Cholesterol (non-HDL-C) at Week 8, Percent Change from Baseline in Lipoprotein (a) (Lp[a]) at Week 8, Percentage of Participants with LDL-C <70 mg/dL and ≥50% Reduction from Baseline at Week 8, Percentage of Participants with LDL-C <55 mg/dL and ≥50% Reduction from Baseline at Week 8
Interventions
Sponsors
Eligibility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Percent Change from Baseline in Low-Density Lipoprotein Cholesterol (LDL-C) at Week 8 (Enlicitide + Rosuvastatin Versus Placebo) | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean Percent Change from Baseline in LDL-C at Week 8, Mean Percent Change from Baseline in Apolipoprotein B (ApoB) at Week 8, Number of Participants with One or More Adverse Events (AEs), Number of Participants who Discontinue Study Drug Due to One or More AEs, Mean Percent Change from Baseline in LDL-C at Week 12, Mean Percent Change from Baseline in Non-High-Density Lipoprotein Cholesterol (non-HDL-C) at Week 8, Percent Change from Baseline in Lipoprotein (a) (Lp[a]) at Week 8, Percentage of Participants with LDL-C <70 mg/dL and ≥50% Reduction from Baseline at Week 8, Percentage of Participants with LDL-C <55 mg/dL and ≥50% Reduction from Baseline at Week 8 | — |
Countries
Hungary, Spain