Remifentanil versus rocuronium for optimizing video laryngoscopy assisted tracheal intubation in patients undergoing general anaesthesia - a multicentre randomised controlled trial The ROCVIDEO trial

Conditions

Adult patients undergoing tracheal intubation using video laryngoscopy.

Brief summary

Safety: A composite of one or more intubation or anaesthesia-related adverse events: Early (< 20 min): Cardiac arrest, anaphylaxis, pulmonary aspiration, serious traumatic airway injury, desaturation, major hemodynamic event, new onset bradycardia, sustained new arrhythmia Late (< 24 h): Death, brain damage including stroke, acute myocardial infarction, ICU admission, re-intubation, postoperative respiratory failure, intraoperative awareness, pneumonia, dental injury, sore throat, or hoarsenes, Efficacy: Prevalence of failed first-pass intubation. Defined as failed tracheal tube delivery after the first attempt to introduce the video laryngoscope into the patient’s mouth.

Ipsen EØ, Lundstrøm LH, Lodenius Å, Fisker G, Hovind MF, Nielsen CL, Oskarsdottir H, Strøm C, Rosenstock CV, Madsen KPD, Wichmann S, Afshari A, Andersen JH, Nedergaard HK, Bill L, Cronhjort M, Mathiesen O, Jakobsen JC, Vested M, Nørskov AK.

2026-07-01

10.1111/aas.70277

Interventions

DRUGRemifentanil Fresenius Kabi

DRUGRocuronium Fresenius Kabi

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Design outcomes

Primary

Measure	Time frame
Safety: A composite of one or more intubation or anaesthesia-related adverse events: Early (< 20 min): Cardiac arrest, anaphylaxis, pulmonary aspiration, serious traumatic airway injury, desaturation, major hemodynamic event, new onset bradycardia, sustained new arrhythmia Late (< 24 h): Death, brain damage including stroke, acute myocardial infarction, ICU admission, re-intubation, postoperative respiratory failure, intraoperative awareness, pneumonia, dental injury, sore throat, or hoarsenes, Efficacy: Prevalence of failed first-pass intubation. Defined as failed tracheal tube delivery after the first attempt to introduce the video laryngoscope into the patient’s mouth.	—

Measure

Time frame

Safety: A composite of one or more intubation or anaesthesia-related adverse events: Early (< 20 min): Cardiac arrest, anaphylaxis, pulmonary aspiration, serious traumatic airway injury, desaturation, major hemodynamic event, new onset bradycardia, sustained new arrhythmia Late (< 24 h): Death, brain damage including stroke, acute myocardial infarction, ICU admission, re-intubation, postoperative respiratory failure, intraoperative awareness, pneumonia, dental injury, sore throat, or hoarsenes, Efficacy: Prevalence of failed first-pass intubation. Defined as failed tracheal tube delivery after the first attempt to introduce the video laryngoscope into the patient’s mouth.

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Countries

Denmark

Outcome results

None listed