as well as the use of inotropes for low cardiac output syndrome., the levels of NT-ProBNP and troponin I will be measured; and its impact on myocardial preservation, through the measurement of the cardiac index intraoperatively and immediately postoperatively, To evaluate the effects of sevoflurane administration intra- (including the period of extracorporeal circulation ischemia) and postoperatively in patients undergoing double valve surgery with respect to propofol in terms of reducing myocardial damage and injury. For this
Conditions
Brief summary
Evaluation variables: Sex, age, Cardiac index, creatinine, N-GAL, Stroke Volume index, heart rate, beats / min, mean arterial pressure, right ventricular end-diastolic pressure, Troponin I, NT-ProBNP, pre/postconditioning enzymes, renal dysfunction, inotropic support, days of ICU stay and circRNA values
Interventions
DRUGPropofol Eignapharma 10 mg/ml Emulsão injetável/para perfusão
Sponsors
Fundacion Publica Andaluza Para La Investigacion De Malaga En Biomedicina Y Salud
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation variables: Sex, age, Cardiac index, creatinine, N-GAL, Stroke Volume index, heart rate, beats / min, mean arterial pressure, right ventricular end-diastolic pressure, Troponin I, NT-ProBNP, pre/postconditioning enzymes, renal dysfunction, inotropic support, days of ICU stay and circRNA values | — |
Countries
Spain
Outcome results
None listed