difficult-to-treat Rheumatoid Arthritis, Refractory
Conditions
Brief summary
The main goal of this study is to find out if BMS-986528 is safe for people with RA by counting how many people have mild and serious side effects after taking BMS-986528
Detailed description
Measure how much BMS-986528 is in the blood at different times after it is given and look at things like the highest amount of BMS-986528 in the blood, how long it takes to reach that amount, and how quickly the body gets rid of it, Measure if BMS-986528 changes the number and types of B cells in the blood, Measure changes in the levels of proteins called immunoglobulins in the blood, Measure if people’s bodies make antibodies against BMS-986528, Check if BMS-986528 helps reduce the symptoms of RA after about 3 months using a score called DAS28-CRP, which measures how much pain and swelling a patient has as well as how much inflammation is in the body and how a patient feels
Interventions
DRUGBMS-986528
DRUGTOCILIZUMAB
Sponsors
Bristol-Myers Squibb Services Unlimited Company
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main goal of this study is to find out if BMS-986528 is safe for people with RA by counting how many people have mild and serious side effects after taking BMS-986528 | — |
Secondary
| Measure | Time frame |
|---|---|
| Measure how much BMS-986528 is in the blood at different times after it is given and look at things like the highest amount of BMS-986528 in the blood, how long it takes to reach that amount, and how quickly the body gets rid of it, Measure if BMS-986528 changes the number and types of B cells in the blood, Measure changes in the levels of proteins called immunoglobulins in the blood, Measure if people’s bodies make antibodies against BMS-986528, Check if BMS-986528 helps reduce the symptoms of RA after about 3 months using a score called DAS28-CRP, which measures how much pain and swelling a patient has as well as how much inflammation is in the body and how a patient feels | — |
Outcome results
None listed