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A single centre parallel-group randomized control trial of Magnetic Resonance Assessment of Variations in Effects of anaesthesia on renaL perfusion in children

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2025-520627-25-00
Enrollment
50
Registered
2025-09-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative Acute Kidney Injury

Brief summary

Differences in RBF, as measured by phase contrast imaging with mpMRI, between propofol and sevoflurane anesthesia.

Detailed description

The difference plasma renin concentration, measured by a blood sample, between propofol and sevoflurane anaesthesia, The difference in relation of RBF to systemic non-invasive blood pressure, between propofol and sevoflurane anaesthesia, Differences in regional and global renal oxygenation, as measured by Blood Oxygen Level Dependent (BOLD) signal via mpMRI, between propofol and sevoflurane anaesthesia., Differences in regional renal tissue perfusion, as measured by arterial spin labelling (ASL) with mpMRI, between propofol and sevoflurane anaesthesia

Interventions

DRUGPROPOFOL
DRUGSEVOFLURANE

Sponsors

Region Uppsala
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
0 Years to 17 Years

Design outcomes

Primary

MeasureTime frame
Differences in RBF, as measured by phase contrast imaging with mpMRI, between propofol and sevoflurane anesthesia.

Secondary

MeasureTime frame
The difference plasma renin concentration, measured by a blood sample, between propofol and sevoflurane anaesthesia, The difference in relation of RBF to systemic non-invasive blood pressure, between propofol and sevoflurane anaesthesia, Differences in regional and global renal oxygenation, as measured by Blood Oxygen Level Dependent (BOLD) signal via mpMRI, between propofol and sevoflurane anaesthesia., Differences in regional renal tissue perfusion, as measured by arterial spin labelling (ASL) with mpMRI, between propofol and sevoflurane anaesthesia

Countries

Sweden

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026