Atopic dermatitis
Conditions
Brief summary
The percentage of patients achieving EASI-75 (≥75% reduction from Baseline in EASI score) at Week 24, the final visit of the study.
Detailed description
Alternative clinically evaluated endpoint measures (IGA ≤1 and≥2 point improvement; DLQI≥4 point improvement; NRS ≥4 point improvement);, Registry-based (EG: SwedAD) PROMS (POEM, MADRS-S, RECAP), Skin physiological outcome measures in the form of EIS in all patients and evaporimetry, Epsilon and TiVi in a subgroup, NMF and Skin lipid sampling (tape stripping in all and biopsy for ToF-SIMS in an adult subgroup, Vitamin D status in blood and skin biopsy (adults only)
Interventions
Sponsors
Region Oestergoetland
Eligibility
Sex/Gender
All
Age
0 Years to 64 Years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of patients achieving EASI-75 (≥75% reduction from Baseline in EASI score) at Week 24, the final visit of the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Alternative clinically evaluated endpoint measures (IGA ≤1 and≥2 point improvement; DLQI≥4 point improvement; NRS ≥4 point improvement);, Registry-based (EG: SwedAD) PROMS (POEM, MADRS-S, RECAP), Skin physiological outcome measures in the form of EIS in all patients and evaporimetry, Epsilon and TiVi in a subgroup, NMF and Skin lipid sampling (tape stripping in all and biopsy for ToF-SIMS in an adult subgroup, Vitamin D status in blood and skin biopsy (adults only) | — |
Outcome results
None listed