Pre- vs. postoperative thromboprophylaxis for liver resection – a prospective, multicentre, randomized controlled trial (PREPOSTEROUS trial)

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-519726-20-00

Acronym

PREPOSTEROUS

Enrollment

500

Registered

2024-12-19

Start date

2022-03-17

Completion date

Unknown

Last updated

2024-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver surgery

Brief summary

Venous thromboembolisms, number of patients, within 30 days from liver resection.

Detailed description

1) Posthepatectomy haemorrhage, any grade in ISGLS classification, number of patients, within 30 days from liver resection 2) Comprehensive Complication Index – score, within 30 days from liver resection 3) Length of postoperative hospital stay, days 4) Total amount of transfused red blood cells, units, during and within 30 days from liver resection

Interventions

DRUGDALTEPARIN

DRUGENOXAPARIN

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Venous thromboembolisms, number of patients, within 30 days from liver resection.	—

Secondary

Measure	Time frame
1) Posthepatectomy haemorrhage, any grade in ISGLS classification, number of patients, within 30 days from liver resection 2) Comprehensive Complication Index – score, within 30 days from liver resection 3) Length of postoperative hospital stay, days 4) Total amount of transfused red blood cells, units, during and within 30 days from liver resection	—

Countries

Norway

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026