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Retinoic acid and sperm production in infertile men

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-519644-33-00
Enrollment
100
Registered
2026-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oligozoospermia

Brief summary

The primary evaluation criterion is sperm production measured after 20 weeks of weekly isotretinoin treatment, compared to that of men who received a placebo

Detailed description

Sperm motility and morphology after 20 weeks of weekly isotretinoin treatment

Interventions

DRUGcomprimés placebo à usage thérapeutique 260mg
DRUGISOTRETINOINE ACNETRAIT 40 mg

Sponsors

Les Hopitaux Universitaires De Strasbourg
Lead SponsorOTHER

Eligibility

Sex/Gender
Male
Age
18 Years to 64 Years

Design outcomes

Primary

MeasureTime frame
The primary evaluation criterion is sperm production measured after 20 weeks of weekly isotretinoin treatment, compared to that of men who received a placebo

Secondary

MeasureTime frame
Sperm motility and morphology after 20 weeks of weekly isotretinoin treatment

Outcome results

None listed

Source: EU CTIS · Data processed: Apr 10, 2026