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A Phase 3b, open-label, multi-center study to assess the immune response and safety of the meningococcal group B vaccine rMenB+OMV NZ when administered to healthy participants aged 10 to 20 years old, who were primed during the first 2 years of life

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-519549-31-00
Acronym
220030
Enrollment
247
Registered
2025-08-11
Start date
2025-09-05
Completion date
Unknown
Last updated
2025-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Invasive meningococcal disease (IMD)

Brief summary

hSBA titers against each MenB indicator strain at Visit 2 (Day 31).

Detailed description

hSBA titers against each MenB indicator strain at Visit 2 (Day 31)., hSBA titers against each MenB indicator strain at Visit 1 (Day 1)., • Occurrence of solicited administration site and systemic events within 7 days following the first vaccination. • Occurrence of any unsolicited AEs within 31 days (including the day of injection) following the first vaccination. • Occurrence of AESI (arthritis), SAEs, AEs leading to withdrawal throughout the study period (Day 1 to Day 31).

Interventions

Sponsors

GlaxoSmithKline Biologicals
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
0 Years to 64 Years

Design outcomes

Primary

MeasureTime frame
hSBA titers against each MenB indicator strain at Visit 2 (Day 31).

Secondary

MeasureTime frame
hSBA titers against each MenB indicator strain at Visit 2 (Day 31)., hSBA titers against each MenB indicator strain at Visit 1 (Day 1)., • Occurrence of solicited administration site and systemic events within 7 days following the first vaccination. • Occurrence of any unsolicited AEs within 31 days (including the day of injection) following the first vaccination. • Occurrence of AESI (arthritis), SAEs, AEs leading to withdrawal throughout the study period (Day 1 to Day 31).

Countries

Finland, Italy, Spain

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026