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L-Thyroxine for the treatment of acute unilateral vestibulopathy (AUVP): a monocentric, double-blind, placebo-controlled trial (T4U)

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-519515-34-00
Enrollment
48
Registered
2026-04-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with acute unilateral vestibulopathy (AUVP)

Brief summary

Disease-related quality of life assessed by the change of the DHI value between inclusion and day 14 post study inclusion.

Detailed description

Disease-related quality of life assessed by change of the DHI value between inclusion and day 7, 45, 60, 90 and 180 post study inclusion, Health-related quality of life (assessed by EQ-5D-5L) at day 7, 14, 45, 60, 90, and 180 post study inclusion., Slow-phase velocity (SPV) of spontaneous nystagmus at day 7, 45, and 180 days after study inclusion, Total postural sway (with eyes closed) at day 7, 45, and 180 post study inclusion, Rate of conversion to secondary functional dizziness at day 180 post study inclusion

Interventions

DRUGL-Thyroxin beta 200 μg Tabletten

Sponsors

Klinikum der Universitaet Muenchen AöR
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Disease-related quality of life assessed by the change of the DHI value between inclusion and day 14 post study inclusion.

Secondary

MeasureTime frame
Disease-related quality of life assessed by change of the DHI value between inclusion and day 7, 45, 60, 90 and 180 post study inclusion, Health-related quality of life (assessed by EQ-5D-5L) at day 7, 14, 45, 60, 90, and 180 post study inclusion., Slow-phase velocity (SPV) of spontaneous nystagmus at day 7, 45, and 180 days after study inclusion, Total postural sway (with eyes closed) at day 7, 45, and 180 post study inclusion, Rate of conversion to secondary functional dizziness at day 180 post study inclusion

Outcome results

None listed

Source: EU CTIS · Data processed: Apr 3, 2026