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Prevention of Group G/C Streptococcus Infections during Labour and postpartum - a randomized controlled multicenter trial (POGSI)

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-519263-18-00
Enrollment
696
Registered
2024-11-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Participants are pregnant women found to carry Group G or C Streptococcus as part of their vaginal-rectal flora in the late pregnancy vaginal-rectal culture routinely taken for GBS screening

Brief summary

A postpartum infection of the mother requiring antibiotic treatment up to 3 months after delivery

Detailed description

Positive blood culture of the mother, mode of delivery, need for blood culture from the newborn, antibiotic treatment of the newborn, transfer to NICU, days in the hospital for the mother and the newborn (lenght of stay after birth/delivery)

Interventions

DRUGClindamycin Fresenius Kabi 150 mg/ml injektioneste
DRUGliuos / infuusiokonsentraatti
DRUGBenzylpenicillin Panpharma 3 g injektio-/infuusiokuiva-aine

Sponsors

University Of Oulu
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Design outcomes

Primary

MeasureTime frame
A postpartum infection of the mother requiring antibiotic treatment up to 3 months after delivery

Secondary

MeasureTime frame
Positive blood culture of the mother, mode of delivery, need for blood culture from the newborn, antibiotic treatment of the newborn, transfer to NICU, days in the hospital for the mother and the newborn (lenght of stay after birth/delivery)

Countries

Finland

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026