Influence Of Zoledronic Acid On Healing After Arthroskopic Repair Of Chronic Rotator Cuff Lesions A Prospective, Randomized, Placebo-Controlled Phase II Trial ZORRO

Status

Not yet recruiting

Phases

Phase 2

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-519082-22-00

Acronym

ZORRO

Enrollment

Registered

2025-01-14

Start date

Unknown

Completion date

Unknown

Last updated

2025-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis, Trauma (rupture of a tendon)

Brief summary

 Tendon integrity 6 months postoperative (no re-rupture/re-rupture)  Tendon integrity 12, 24 and 60 months postoperative (no re-rupture/re-rupture)

Detailed description

Fatty muscle infiltration, shoulder abduction and adduction, shoulder anteversion and retroversion, shoulder rotation internal and external, shoulder strength, pain evaluation, Constant-Murley-Score, American Shoulder and Elbow Surgeons Score, Subjective Shoulder Value

Interventions

DRUGELECTROLYTES

DRUGZOLEDRONIC ACID

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
 Tendon integrity 6 months postoperative (no re-rupture/re-rupture)  Tendon integrity 12, 24 and 60 months postoperative (no re-rupture/re-rupture)	—

Secondary

Measure	Time frame
Fatty muscle infiltration, shoulder abduction and adduction, shoulder anteversion and retroversion, shoulder rotation internal and external, shoulder strength, pain evaluation, Constant-Murley-Score, American Shoulder and Elbow Surgeons Score, Subjective Shoulder Value	—

Countries

Austria

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026