Prospective phase IIb study to evaluate the efficacy of laparoscopic electrochemotherapy in the treatment of locally advanced pancreatic cancer - ECT-LAPC Laparoscopic

Status

Not yet recruiting

Phases

Phase 2

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-519067-17-00

Enrollment

Registered

2024-12-02

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Locally Advanced Pancreatic Cancer

Brief summary

Increase in the objective response rate of the treated lesion in the treatment arm compared to the control arm

Detailed description

Evaluate the effect of ECT on disease progression-free time and survival., Evaluate the impact of ECT on quality of life, with particular attention to its effect on pain, Assess the toxicity associated with Electrochemotherapy treatment., Evaluate the conversion rate of the disease from locally advanced to resectable between the two arms.

Interventions

DRUGBLEOPRIM 15 mg polvere per soluzione iniettabile

DRUGFluorouracil 50 mg/ml Solution for Injection or Infusion

DRUGLEDERFOLIN 25 mg Polvere per soluzione iniettabile per uso endovenoso

DRUGCAMPTO 20 mg/mL concentrate for solution for infusion

DRUGOxaliplatin 5 mg/ml Concentrate for Solution for infusion

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Increase in the objective response rate of the treated lesion in the treatment arm compared to the control arm	—

Secondary

Measure	Time frame
Evaluate the effect of ECT on disease progression-free time and survival., Evaluate the impact of ECT on quality of life, with particular attention to its effect on pain, Assess the toxicity associated with Electrochemotherapy treatment., Evaluate the conversion rate of the disease from locally advanced to resectable between the two arms.	—

Countries

Italy

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026