The effect of additional pre-extubational loading dose of caffeine-citrate

Status

Not yet recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-519041-29-02

Acronym

NEOKOFF22

Enrollment

226

Registered

2025-01-15

Start date

Unknown

Completion date

Unknown

Last updated

2025-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extubation failure and bronchopulmonary dysplasia

Brief summary

Reintubation.

Detailed description

Frequency of apnoeas. Side effects (elevated heart rate, elevated blood pressure, gastric residuals) Necrotizing enterocolitis. Bronchopulmonary dysplasia. The progression or development of intraventricular hemorrhage or periventricular leukomalacia. Neurodevelopmental outcome.

Interventions

DRUGCAFFEINE CITRATE

Eligibility

Sex/Gender

All

Age

0 Years to 17 Years

Design outcomes

Primary

Measure	Time frame
Reintubation.	—

Secondary

Measure	Time frame
Frequency of apnoeas. Side effects (elevated heart rate, elevated blood pressure, gastric residuals) Necrotizing enterocolitis. Bronchopulmonary dysplasia. The progression or development of intraventricular hemorrhage or periventricular leukomalacia. Neurodevelopmental outcome.	—

Countries

Hungary

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026