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Body Weight Adjusted Clopidogrel treatment in patients with CORonary artery Disease (BW-ACCORD)

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-518890-33-00
Enrollment
80
Registered
2024-11-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic coronary syndrome

Brief summary

Level of platelet reactivity, measured as Platelet Reaction Unit, as measured by the VerifyNow system

Detailed description

To determine if the CYP2C19 genotype has additional effect on the platelet reactivity in the different treatment groups., To assess the difference between PRU values in the high bodyweight/BMI group during clopidogrel treatment and prasugrel treatment., To assess possible confounders for HTPR., Mortality (and cause of mortality), Myocardial infarction, Stent thrombosis, Revascularization, Stroke, Bleedings, To correlate the measured body fat percentages with PRU values.

Interventions

Sponsors

Sint Antonius Ziekenhuis Stichting
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Level of platelet reactivity, measured as Platelet Reaction Unit, as measured by the VerifyNow system

Secondary

MeasureTime frame
To determine if the CYP2C19 genotype has additional effect on the platelet reactivity in the different treatment groups., To assess the difference between PRU values in the high bodyweight/BMI group during clopidogrel treatment and prasugrel treatment., To assess possible confounders for HTPR., Mortality (and cause of mortality), Myocardial infarction, Stent thrombosis, Revascularization, Stroke, Bleedings, To correlate the measured body fat percentages with PRU values.

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026