autoimmune disorders, joint disorders synonym: Still's disease, systemic JIA
Conditions
Brief summary
* The total (mean/median) number of injections of anakinra per patient necessary to achieve and maintain clinically inactive disease during the first year of treatment.
Detailed description
* The number of patients with *clinically inactive disease* without medication at time point 1 year., * The total number of disease flares during or after tapering and stop of therapy in the first year;, * The number of patients with remission off medication at time point 2 years;, * The number of patients needing to switch treatment because of treatment failure during the first year (to calculate reduction in treatment costs), * The number of (serious) adverse events in the first year.
Interventions
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Sex/Gender
All
Age
0 Years to 17 Years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| * The total (mean/median) number of injections of anakinra per patient necessary to achieve and maintain clinically inactive disease during the first year of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| * The number of patients with *clinically inactive disease* without medication at time point 1 year., * The total number of disease flares during or after tapering and stop of therapy in the first year;, * The number of patients with remission off medication at time point 2 years;, * The number of patients needing to switch treatment because of treatment failure during the first year (to calculate reduction in treatment costs), * The number of (serious) adverse events in the first year. | — |
Countries
Netherlands
Outcome results
None listed