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Phase II: 68Ga-NODAGA-E[c(RGDyK)]2 Angiogenese PET for imaging angiogenesis in ischemic heart disease

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-518640-20-00
Enrollment
42
Registered
2025-01-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic ischemic heart disease

Brief summary

Characterize the difference in myocardial angiogenesis measured with RGD-PET uptake before and after coronary revascularization

Detailed description

Correlation between myocardial angiogenic response (determined by RGD-PET) and changes in myocardial perfusion (82Rb-PET) after coronary revascularization., Correlation between myocardial angiogenic response after 3 weeks (determined by RGD-PET) and functional recovery and final infarct (18F-FDG-PET) size 6-8 weeks after coronary revascularization, Correlation between myocardial angiogenic response (determined by RGD-PET) and viability (18-F-FDG) before and after coronary revascularization

Interventions

DRUG[68Ga]NODAGA-E[c(RGDyK)]2

Sponsors

Rigshospitalet
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Characterize the difference in myocardial angiogenesis measured with RGD-PET uptake before and after coronary revascularization

Secondary

MeasureTime frame
Correlation between myocardial angiogenic response (determined by RGD-PET) and changes in myocardial perfusion (82Rb-PET) after coronary revascularization., Correlation between myocardial angiogenic response after 3 weeks (determined by RGD-PET) and functional recovery and final infarct (18F-FDG-PET) size 6-8 weeks after coronary revascularization, Correlation between myocardial angiogenic response (determined by RGD-PET) and viability (18-F-FDG) before and after coronary revascularization

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026