Charcot, diabetes
Conditions
Brief summary
Time to cession of total contact cast (Days) in combination with curation of foot fractures (by independent radiologist) upon denosumab treatment at baseline, 3,6 and 9 months in diabetes patients with proven Charcot foot (blindly analysed by prof Maas, dept. of Radiology AMC)
Detailed description
Prevention of foot deformation (as determined by plantar pressure measurements before and in diabetes patients with radiologically proven Charcot foot. Also changes in volume (water displacement) and foot temperature of both feet as well as clinical risk score will be determined at these time points.
Interventions
DRUGSALINE
DRUGDENOSUMAB
Sponsors
Amsterdam UMC Stichting
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to cession of total contact cast (Days) in combination with curation of foot fractures (by independent radiologist) upon denosumab treatment at baseline, 3,6 and 9 months in diabetes patients with proven Charcot foot (blindly analysed by prof Maas, dept. of Radiology AMC) | — |
Secondary
| Measure | Time frame |
|---|---|
| Prevention of foot deformation (as determined by plantar pressure measurements before and in diabetes patients with radiologically proven Charcot foot. Also changes in volume (water displacement) and foot temperature of both feet as well as clinical risk score will be determined at these time points. | — |
Countries
Netherlands
Outcome results
None listed