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Tittle: Effects of intravenous administered iron in non-anemic iron deficient patients with colorectal cancer. A double blinded clinical randomized trial.

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-518517-26-00
Enrollment
134
Registered
2024-11-15
Start date
2024-10-10
Completion date
Unknown
Last updated
2024-11-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iron deficiency

Brief summary

Changes in cellular respiration (VO2max at the Anaerobic Threshold) measured by the gold standard Cardio Pulmonary Exercise Testing (CPET)., The preoperative change in the Neutrophil to Lymphocyte Ratio (NLR), The up and downregulation of immune function at the invasive front of the tumor, measured by the Nanostring™ PanCancer Immune® profiling panel

Detailed description

The patients subjective description of physical capacity measured by the Fatique Severity Score questionnaire, Treatment characteristics such as: Adverse events, serious adverse events, blood transfusions, changes in transferrin, ferritin, transferrin saturation, iron, hemoglobin and phosphate, length of stay, infectious complications measured by the comprehensive complication index and quality of recovery-15 during the admission, One and five year survival rates and recurrence rates.

Interventions

Sponsors

Region Sjaelland
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Changes in cellular respiration (VO2max at the Anaerobic Threshold) measured by the gold standard Cardio Pulmonary Exercise Testing (CPET)., The preoperative change in the Neutrophil to Lymphocyte Ratio (NLR), The up and downregulation of immune function at the invasive front of the tumor, measured by the Nanostring™ PanCancer Immune® profiling panel

Secondary

MeasureTime frame
The patients subjective description of physical capacity measured by the Fatique Severity Score questionnaire, Treatment characteristics such as: Adverse events, serious adverse events, blood transfusions, changes in transferrin, ferritin, transferrin saturation, iron, hemoglobin and phosphate, length of stay, infectious complications measured by the comprehensive complication index and quality of recovery-15 during the admission, One and five year survival rates and recurrence rates.

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026