Prospective, open-label, non-randomized, single-arm, dose titration study to investigate the efficacy and safety of IncobotulinumtoxinA in children deemed to require a total body dose up to 22U/kg (maximum dose 550U) during the study period for the treatment of upper and lower limb spasticity due to cerebral palsy. PROTOCOL CODE: INCIPIT

multifocal spasticity of the upper and lower limb due to cerebral palsy

Changes in Ashworth scale values between the injection cycle baseline visits and the control ones of respective injection cycle (single interventional effect)

Efficacy endpoint: Scala di Ashworth, REsistance to PAssive movement Scale (REPAS), The GMFCS, The visual analog scale (VAS), The Goal Attainment scale (GAS), The Global Assessment of Efficacy, Safety endpoints: Values of blood pressure, heart rate, and respiratory rate, Values of Body Weight, adverse events, The Global Assessment of Tolerability

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