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Vascular changes in basal cell carcinoma undergoing electrochemotherapy or photodynamic therapy - assessed with optical coherence tomography

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-518228-63-01
Enrollment
56
Registered
2024-11-25
Start date
Unknown
Completion date
2025-06-27
Last updated
2024-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

basal cell carcinoma

Brief summary

The primary objective is to investigate the microvascular changes in BCC during non-surgical treatment using D-OCT. The occlusion (diameter of the widest vessel at a given depth), reduction of the proportion of patent vessels at 0, 150, 300 and 500 micrometer depth will be assessed relative to pre-treatment and posttreatment levels according to visits.

Detailed description

To assess any predictors (thickness, density, attenuation and vascular pattern) in clinical outcome of of BCC undergoing non-surgical therapy by means of using D-OCT. To evaluate the quality of life in patients undergoing these treatments by SCQoL. To evaluate hyperpigmentation as a side effect of bleomycin

Interventions

DRUGBLEOMYCIN

Sponsors

Region Sjaelland
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
The primary objective is to investigate the microvascular changes in BCC during non-surgical treatment using D-OCT. The occlusion (diameter of the widest vessel at a given depth), reduction of the proportion of patent vessels at 0, 150, 300 and 500 micrometer depth will be assessed relative to pre-treatment and posttreatment levels according to visits.

Secondary

MeasureTime frame
To assess any predictors (thickness, density, attenuation and vascular pattern) in clinical outcome of of BCC undergoing non-surgical therapy by means of using D-OCT. To evaluate the quality of life in patients undergoing these treatments by SCQoL. To evaluate hyperpigmentation as a side effect of bleomycin

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026