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Lung Microbiota’s evolution after use of Nitrous Oxide on pediatric patient needing airway samples - MicroNO

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-518197-14-00
Acronym
29BRC23.0238
Enrollment
40
Registered
2025-02-12
Start date
2025-09-24
Completion date
Unknown
Last updated
2025-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric respiratory disorder

Brief summary

Pulmonary bacterial biodiversity assessed using quantitative indices such as alpha diversity and beta diversity calculated for good-quality respiratory samples

Detailed description

Assessment of sputum tolerance induced by -The use of age-appropriate anxiety scores (mYPAS-SF, cf. appendix 2) -Likert scales to assess the MKDE practitioner's feelings (cf. Appendix 3) -A numerical scale from 0 to 10 to assess the parents' feelings, Quality of samples according to cytological score, Collection of adverse events, Difference between ECBC with and without MEOPA (direct examination, count and culture), Catalog of bacterial taxa identified by 16S v3-v4 targeted metagenomics.

Interventions

DRUGgaz medicinal comprimé

Sponsors

Centre Hospitalier Regional Et Universitaire De Brest
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
0 Years to 17 Years

Design outcomes

Primary

MeasureTime frame
Pulmonary bacterial biodiversity assessed using quantitative indices such as alpha diversity and beta diversity calculated for good-quality respiratory samples

Secondary

MeasureTime frame
Assessment of sputum tolerance induced by -The use of age-appropriate anxiety scores (mYPAS-SF, cf. appendix 2) -Likert scales to assess the MKDE practitioner's feelings (cf. Appendix 3) -A numerical scale from 0 to 10 to assess the parents' feelings, Quality of samples according to cytological score, Collection of adverse events, Difference between ECBC with and without MEOPA (direct examination, count and culture), Catalog of bacterial taxa identified by 16S v3-v4 targeted metagenomics.

Countries

France

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026