post-acute sequelae of COVID-19
Conditions
Brief summary
TBRLung (Target to background ratio of the lung) differences per group
Detailed description
SUVmean and SUVmax of both paravertebral muscles, [68Ga]FAPI uptake (SUVmean) vs % of ground galss opacities (GGO) on high resolution CT, [68Ga]FAPI uptake (SUVmean) related to the outcome of multiple questionnaires., [68Ga]FAPI uptake (SUVmean) related to patience health metrics (lung function and 6-MWT), [68Ga]FAPI uptake (SUVmean) related to biology (circulating extra cellular matrix fragments, circulating soluble FAP, inflammatory blood markers and systemic and upper respiratory tract cellular phenotypes)
Interventions
DRUG[68Ga]FAPI-46
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TBRLung (Target to background ratio of the lung) differences per group | — |
Secondary
| Measure | Time frame |
|---|---|
| SUVmean and SUVmax of both paravertebral muscles, [68Ga]FAPI uptake (SUVmean) vs % of ground galss opacities (GGO) on high resolution CT, [68Ga]FAPI uptake (SUVmean) related to the outcome of multiple questionnaires., [68Ga]FAPI uptake (SUVmean) related to patience health metrics (lung function and 6-MWT), [68Ga]FAPI uptake (SUVmean) related to biology (circulating extra cellular matrix fragments, circulating soluble FAP, inflammatory blood markers and systemic and upper respiratory tract cellular phenotypes) | — |
Countries
Netherlands
Outcome results
None listed