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Testosterone Replacement Therapy in Women with Turner Syndrome – Endocrine, Cardiovascular, Physiological, Neurocognitive and Genomic effects

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-517755-12-00
Enrollment
50
Registered
2025-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Turner Syndrome

Brief summary

Changes in body composition examined by total body dual-energy x-ray absorptiometry (DXA-scan) including bone mass, visceral and subcutaneous fat mass, and lean muscle mass, as well as measures of abdominal circumference and weight.

Detailed description

Changes in quality of life, Changes in inflammatory markers, Changes in sexual function, Changes in intramuscular sex hormone levels, Changes in blood volume and hemoglobin mass, Changes in coagulation parameters, Changes in metabolic parameters, Changes in neurocognitive function, Changes in hypothalamus structure, Changes in VO2-max, physical activity, muscle function and strength

Interventions

DRUGISOPROPYL MYRISTATE
DRUGANDROGEL 25 mg
DRUGETHANOL (96 PER CENT)

Sponsors

Region Midtjylland
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Design outcomes

Primary

MeasureTime frame
Changes in body composition examined by total body dual-energy x-ray absorptiometry (DXA-scan) including bone mass, visceral and subcutaneous fat mass, and lean muscle mass, as well as measures of abdominal circumference and weight.

Secondary

MeasureTime frame
Changes in quality of life, Changes in inflammatory markers, Changes in sexual function, Changes in intramuscular sex hormone levels, Changes in blood volume and hemoglobin mass, Changes in coagulation parameters, Changes in metabolic parameters, Changes in neurocognitive function, Changes in hypothalamus structure, Changes in VO2-max, physical activity, muscle function and strength

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026