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LIDOCRIT : Effect of continuous intravenous LIDOCaine on discomfort in postoperative CRITical care inpatients

Status
Not yet recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-517749-15-00
Acronym
35RC22_8943_LIDOCRIT
Enrollment
246
Registered
2025-06-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative critical care

Brief summary

Overall score on the IPREA questionnaire (Inconforts of REAnimation Patients with 18 items) carried out within 24 hours of discharge from critical care or, failing that, within 24 hours of the 30th day of hospitalisation in critical care

Detailed description

Result per item of 8 items of the IPREA score, carried out within 24 hours before discharge from critical care or, failing that, within 24 hours before the 30th day of hospitalisation in critical care: - Noise - Thirst - Pain - Medical devices (catheters, intubation tubes, etc.) - Sleepiness - Dyspnoea - Anxiety - Depression, Cumulative opiate consumption over the first 6 post-operative days (in equivalent mg of IV morphine, or µg of Remifentanil or µg of Sufentanil), The duration of invasive mechanical ventilation in critical care (over a maximum period of 30 days post-operatively), Re-intubation within 48 hours of extubation (up to discharge from critical care or, failing that, up to the 30th postoperative day), The duration of sedation (until discharge from critical care or, failing that, the 30th postoperative day maximum), The length of stay in critical care, including, in the event of transfer, the stay in critical care in the transfer hospital, over a maximum period of 30 post-operative days, The total length of hospital stay including, in the event of transfer, the stay in the transfer hospital, over a maximum period of 30 post-operative days, Vital status on the 30th postoperative day, The incidence of care-associated pneumonia (RFE SFAR/SRLF 2017 ‘Care-associated pneumonia’ criteria in appendix) during the critical care stay over a maximum of 30 post-operative days, The incidence of delirium (measured by CAM ICU) during the critical care stay over a maximum of 30 days post-operatively, The incidence of adverse reactions attributable to lidocaine over the duration of treatment administration and 24 hours after the end of treatment administration

Interventions

Sponsors

Centre Hospitalier Universitaire De Rennes
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Overall score on the IPREA questionnaire (Inconforts of REAnimation Patients with 18 items) carried out within 24 hours of discharge from critical care or, failing that, within 24 hours of the 30th day of hospitalisation in critical care

Secondary

MeasureTime frame
Result per item of 8 items of the IPREA score, carried out within 24 hours before discharge from critical care or, failing that, within 24 hours before the 30th day of hospitalisation in critical care: - Noise - Thirst - Pain - Medical devices (catheters, intubation tubes, etc.) - Sleepiness - Dyspnoea - Anxiety - Depression, Cumulative opiate consumption over the first 6 post-operative days (in equivalent mg of IV morphine, or µg of Remifentanil or µg of Sufentanil), The duration of invasive mechanical ventilation in critical care (over a maximum period of 30 days post-operatively), Re-intubation within 48 hours of extubation (up to discharge from critical care or, failing that, up to the 30th postoperative day), The duration of sedation (until discharge from critical care or, failing that, the 30th postoperative day maximum), The length of stay in critical care, including, in the event of transfer, the stay in critical care in the transfer hospital, over a maximum period of 30 post-o

Countries

France

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026