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Filling bone erosions: a longitudinal multicentric HR-pQCT study of subcutaneous tocilizumab in rheumatoid arthritis

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-517686-17-01
Acronym
CHRO-2014-03
Enrollment
60
Registered
2025-01-02
Start date
2016-06-30
Completion date
Unknown
Last updated
2025-01-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis

Brief summary

Bone erosion change of width, depth and volume measured by HRpQCT after 12 months of subcutaneous tocilizumab

Detailed description

Number of participants with associated factors with erosion changes by HRpQCT (Associated therapeutic, clinical and biological response )ultrasound ...), Changes of Bone mineral density by DXA at the lumbar spine and proximal femur, Correlation Between clinical activity measured by various indices (Disease Activity Score 28, Clinical Disease Activity Iindex , Simplify Disease Activity Index , American College of Rheumatology - European League against Rheumatism: ACR EULAR) and ultrasound data., Changes of bone microarchitecture by tibia HRpQCT

Interventions

Sponsors

Centre Hospitalier Universitaire D Orleans
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Bone erosion change of width, depth and volume measured by HRpQCT after 12 months of subcutaneous tocilizumab

Secondary

MeasureTime frame
Number of participants with associated factors with erosion changes by HRpQCT (Associated therapeutic, clinical and biological response )ultrasound ...), Changes of Bone mineral density by DXA at the lumbar spine and proximal femur, Correlation Between clinical activity measured by various indices (Disease Activity Score 28, Clinical Disease Activity Iindex , Simplify Disease Activity Index , American College of Rheumatology - European League against Rheumatism: ACR EULAR) and ultrasound data., Changes of bone microarchitecture by tibia HRpQCT

Countries

France

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026