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Synaptic density and tau pathology in Alzheimer’s disease (SYNAPSE)

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-517636-22-00
Enrollment
30
Registered
2024-12-10
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease

Brief summary

Quantification of brain regional [18F]SynVesT-1 uptake (synaptic density) and regional [ 18F]flortaucipir uptake (tau)

Detailed description

association between [18F]Flortaucipir (tau) binding and [18F]SynVesT-1 (synaptic density) binding

Interventions

DRUG18F-Synvest-1

Sponsors

Amsterdam UMC Stichting
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Quantification of brain regional [18F]SynVesT-1 uptake (synaptic density) and regional [ 18F]flortaucipir uptake (tau)

Secondary

MeasureTime frame
association between [18F]Flortaucipir (tau) binding and [18F]SynVesT-1 (synaptic density) binding

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026