Tau PET imaging in cognitively normal elderly subjects: A twin approach

Status

Not yet recruiting

Phases

Phase 2

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-517634-17-01

Enrollment

Registered

2024-12-02

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy controls (investigating preclinical Alzheimer's Disease)

Brief summary

1. To investigate the effect of amyloid status(positive versus negative) on (longitudinal) [18F]AV‐ 1451 accumulation in cognitively normal individuals. 2. To investigate the contribution of genetic factors and non‐genetic factors to (longitudinal) tau accumulation and its interaction with amyloid accumulation

Interventions

DRUGFlortaucipir

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Design outcomes

Primary

Measure	Time frame
1. To investigate the effect of amyloid status(positive versus negative) on (longitudinal) [18F]AV‐ 1451 accumulation in cognitively normal individuals. 2. To investigate the contribution of genetic factors and non‐genetic factors to (longitudinal) tau accumulation and its interaction with amyloid accumulation	—

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026