Skip to content

A Phase II, open label, single arm, multicentre study on THOracic Radiotherapy in Extensive Stage SCLC patients submitted to first line CHT-RT plus Durvalumab (MEDI4736)

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-517445-13-00
Enrollment
94
Registered
2024-11-11
Start date
Unknown
Completion date
2025-01-27
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extended stage small cell lung cancer patients confirmed histologically in full, partial or stable response after platinum-etoposide chemo-immunotherapy candidate to maintenance immunotherapy with Durvalumab.

Brief summary

The assessment of 12-Months progression-free survival (PFS, defined as time from enrollment to the date of objective disease progression both locoregionally and/or systemically) or death for any cause in absence of progression of disease) in extensive stage SCLC patients

Detailed description

Overall survival, Loco-regional control, Metastasis-free survival, Overall response rate, Acute toxicity, Late toxicity, General security profile, Quality of life

Interventions

DRUGDURVALUMAB

Sponsors

Azienda Ospedaliero Universitaria Di Modena
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
The assessment of 12-Months progression-free survival (PFS, defined as time from enrollment to the date of objective disease progression both locoregionally and/or systemically) or death for any cause in absence of progression of disease) in extensive stage SCLC patients

Secondary

MeasureTime frame
Overall survival, Loco-regional control, Metastasis-free survival, Overall response rate, Acute toxicity, Late toxicity, General security profile, Quality of life

Countries

Italy

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026