Nitrous oxide detection - A study in healthy volunteers to help victims of nitrous oxide related crimes

Conditions

Nitrous oxide intoxication

Brief summary

Time from end of inhalation of study medication to N2O-concentration in blood is no longer statistically significantly increased in the active treatment group compared to the placebo group

Detailed description

Time until N2O-concentration in exhaled breath is no longer statistically significantly increased in the active treatment group compared to the placebo group, Time until N2O-concentration in oral fluid and urine is no longer statistically significantly increased in the active treatment group compared to the placebo group., Time until N2O screening breathalyzer is no longer capable of N2O detection., Time until the longest detectable possible biomarker in blood or urine is no longer up- or downregulated in the active treatment group compared to the placebo group., Time until formiminoglutamic acid is no longer statistically significantly increased in the active treatment group compared to the and placebo group., Verifying that concentration of N2O and possible biomarkers can detected by routine screening at Department of Forensic Medicine, Aarhus University.

Related papers

No related papers found yet.

Interventions

DRUGPARACETAMOL

DRUGOXYGEN

DRUGNITROUS OXIDE

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Design outcomes

Primary

Measure	Time frame
Time from end of inhalation of study medication to N2O-concentration in blood is no longer statistically significantly increased in the active treatment group compared to the placebo group	—

Secondary

Measure	Time frame
Time until N2O-concentration in exhaled breath is no longer statistically significantly increased in the active treatment group compared to the placebo group, Time until N2O-concentration in oral fluid and urine is no longer statistically significantly increased in the active treatment group compared to the placebo group., Time until N2O screening breathalyzer is no longer capable of N2O detection., Time until the longest detectable possible biomarker in blood or urine is no longer up- or downregulated in the active treatment group compared to the placebo group., Time until formiminoglutamic acid is no longer statistically significantly increased in the active treatment group compared to the and placebo group., Verifying that concentration of N2O and possible biomarkers can detected by routine screening at Department of Forensic Medicine, Aarhus University.	—

Measure

Time frame

Time until N2O-concentration in exhaled breath is no longer statistically significantly increased in the active treatment group compared to the placebo group, Time until N2O-concentration in oral fluid and urine is no longer statistically significantly increased in the active treatment group compared to the placebo group., Time until N2O screening breathalyzer is no longer capable of N2O detection., Time until the longest detectable possible biomarker in blood or urine is no longer up- or downregulated in the active treatment group compared to the placebo group., Time until formiminoglutamic acid is no longer statistically significantly increased in the active treatment group compared to the and placebo group., Verifying that concentration of N2O and possible biomarkers can detected by routine screening at Department of Forensic Medicine, Aarhus University.

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Countries

Denmark

Outcome results

None listed