migraine
Conditions
Brief summary
Difference in neurotransmitter level in the occipital cortex before and after 12 weeks of CGRP antibody treatment in the interventional group compared to the control group assessed by MR spectroscopy at baseline and FU visit 3.
Detailed description
Comparison of neurochemical/metabolic changes between study participants with migraine with and without aura., Change in migraine frequency and intensity over the treatment period assessed by MIDAS and HIT 6 questionnaire, Correlation between the neurochemical changes and the clinical symptoms (e.g. migraine frequency, intensity or duration)
Interventions
Sponsors
Medizinische Universitaet Innsbruck
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in neurotransmitter level in the occipital cortex before and after 12 weeks of CGRP antibody treatment in the interventional group compared to the control group assessed by MR spectroscopy at baseline and FU visit 3. | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of neurochemical/metabolic changes between study participants with migraine with and without aura., Change in migraine frequency and intensity over the treatment period assessed by MIDAS and HIT 6 questionnaire, Correlation between the neurochemical changes and the clinical symptoms (e.g. migraine frequency, intensity or duration) | — |
Countries
Austria
Outcome results
None listed