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A Phase 1/2, Open-label Study of Nivolumab Monotherapy or Nivolumab combined with Ipilimumab in Subjects with Advanced or Metastatic Solid Tumors

Status
Completed
Phases
Phase 1Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-516540-25-00
Acronym
CA209-032
Enrollment
83
Registered
2024-09-12
Start date
2013-12-11
Completion date
2024-11-18
Last updated
2024-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced or metastatic solid tumors: 1) Triple Negative Breast Cancer (TNBC) 2) Gastric Cancer (GC) 3) Pancreatic Cancer (PC) 4) Small Cell Lung Cancer (SCLC). 5) Bladder Cancer (BC) 6) Ovarian Cancer (OC)

Brief summary

Objective response rate (ORR) in all assigned subjects as determined by the investigators. ORR is defined as the number of subjects with a confirmed best overall response (BOR) of complete response (CR) or partial response (PR) divided by the number of assigned subjects

Detailed description

Rate of treatment-related adverse events (AEs) leading to drug discontinuations during the first 12 weeks of treatment, Progression Free Survival (PFS), Overall Survival (OS)

Interventions

DRUGOPDIVO 10 mg/mL concentrate for solution for infusion.
DRUGIpilimumab

Sponsors

Bristol Myers Squibb International Corporation
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Objective response rate (ORR) in all assigned subjects as determined by the investigators. ORR is defined as the number of subjects with a confirmed best overall response (BOR) of complete response (CR) or partial response (PR) divided by the number of assigned subjects

Secondary

MeasureTime frame
Rate of treatment-related adverse events (AEs) leading to drug discontinuations during the first 12 weeks of treatment, Progression Free Survival (PFS), Overall Survival (OS)

Countries

Germany

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026