Prospective diagnostic performance of PET/CT using the novel fibroblast imaging tracer 18F-AlF-FAPI-74 versus standard of care 18F-FDG in inflammatory disorders.

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-516464-28-00

Enrollment

135

Registered

2025-05-08

Start date

2025-08-27

Completion date

Unknown

Last updated

2025-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fever of unknown origin/Inflammation of unknown origin IgG4-related disease Axial Spondyloartrhitis

Brief summary

1. FUO/IUO: sensitivity for evaluating the origin of fever and/or inflammation. 2. sensitivity for diagnosing IgG4-RD in patients with suspected IgG4-RD and assessment of disease extent in patients with confirmed IgG4-RD using the organ detection ratio. 3. AxSpA: sensitivity and specificity in differentiating inflammatory back pain from mechanical back pain.

Interventions

None listed

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
1. FUO/IUO: sensitivity for evaluating the origin of fever and/or inflammation. 2. sensitivity for diagnosing IgG4-RD in patients with suspected IgG4-RD and assessment of disease extent in patients with confirmed IgG4-RD using the organ detection ratio. 3. AxSpA: sensitivity and specificity in differentiating inflammatory back pain from mechanical back pain.	—

Countries

Belgium

Outcome results