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A MULTICENTER, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFECTS OF TASIMELTEON VS. PLACEBO IN TREATING PEDIATRIC INSOMNIA

Status
Not yet recruiting
Phases
Phase 3
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-516411-24-00
Acronym
VP-VEC-162-3108
Enrollment
50
Registered
2025-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insomnia Disorder

Brief summary

Sleep Latency as measured by daily sleep diary

Detailed description

Nighttime subjective sleep parameters as measured by daily sleep diary, Patient Global Impression of Change scale (PGI-C), Clinical Global Impression of Change scale (CGI-C), Caregiver Global Impression of Change scale (CaGI-C), Epworth Sleepiness Scale for Children and Adolescents (ESS-CHAD), Sheehan Disability Scale for Pediatrics and Adolescents (SDS-P/A), Aberrant Behavior Checklist (ABC), Actigraphy parameters, Tasimelteon pharmacokinetics (PK) in 2-year-old participants

Interventions

DRUGPlacebo liquid formulation will be indistinguishable from its tasimelteon counterpart and will be administered in the same way.
DRUGTasimelteon

Sponsors

Vanda Pharmaceuticals Netherlands B.V., Vanda Pharmaceuticals Inc.
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
0 Years to 17 Years

Design outcomes

Primary

MeasureTime frame
Sleep Latency as measured by daily sleep diary

Secondary

MeasureTime frame
Nighttime subjective sleep parameters as measured by daily sleep diary, Patient Global Impression of Change scale (PGI-C), Clinical Global Impression of Change scale (CGI-C), Caregiver Global Impression of Change scale (CaGI-C), Epworth Sleepiness Scale for Children and Adolescents (ESS-CHAD), Sheehan Disability Scale for Pediatrics and Adolescents (SDS-P/A), Aberrant Behavior Checklist (ABC), Actigraphy parameters, Tasimelteon pharmacokinetics (PK) in 2-year-old participants

Countries

Germany, Poland

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026