The effect of Oxygen sUppleTion on vascular resistance and FLOW: the OUTFLOW study

Status

Not yet recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-516279-34-00

Acronym

PaNaMa code: 113071

Enrollment

Registered

2024-10-31

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Microvascular Dysfunction, Heart Failure, Hypoxia, Pulmonary Hypertension

Brief summary

CO (l/min) at 10 minutes after the start of each intervention

Detailed description

CO (l/min) at baseline and after 5 minutes of each intervention, Q (ml/min), R (Woods Units), PAWP (mmHg), PVR (mmHg/l/min) and SVR (mmHg/l/min) at baseline and 5 and 10 minutes after each intervention, Epicardial and microvascular vasospasm at 10 minutes after the start of each intervention, Chronological order of changes in CO, Q, R, PAWP, PVR and SVR

Interventions

DRUGConoxia® Vloeibaar

DRUG100% v/v

DRUGmedicinaal gas

DRUGcryogeen

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
CO (l/min) at 10 minutes after the start of each intervention	—

Secondary

Measure	Time frame
CO (l/min) at baseline and after 5 minutes of each intervention, Q (ml/min), R (Woods Units), PAWP (mmHg), PVR (mmHg/l/min) and SVR (mmHg/l/min) at baseline and 5 and 10 minutes after each intervention, Epicardial and microvascular vasospasm at 10 minutes after the start of each intervention, Chronological order of changes in CO, Q, R, PAWP, PVR and SVR	—

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026