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Venetoclax after TKI to target persisting stem cells in CML

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-516214-38-00
Acronym
VARIANT
Enrollment
10
Registered
2024-10-15
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Myeloid Leukemia

Brief summary

Reduction of BCR::ABL1 stem cells measured by quantitative genomic PCR in bone marrow after venetoclax administration

Interventions

DRUGVENETOCLAX

Sponsors

Friedrich-Schiller-Universitaet Jena
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Reduction of BCR::ABL1 stem cells measured by quantitative genomic PCR in bone marrow after venetoclax administration

Countries

Germany

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026